The German second seed has never been beyond the fourth round of a major but he at least equalled that record as he fought back from a set and a break down - and saved match point in the fifth - to move into the last-16 at Roland Garros for the first time.
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The 2018 French Open quarter-finals began to take shape on Sunday as Alexander Zverev beat Karen Khachanov to progress past the fourth round and will face Dominic Thiem in the next phase of the competition.
Zverev started the final set in fine fashion as he consolidated an immediate break with a serviced hold and avoided facing any break points to secure a notable success.
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The victory was his first on Court Philippe Chatrier.
Buzarnescu, a 30-year-old Romanian with a doctorate in sports sciences who had never won a Grand Slam match before this week, downed Ukraine´s fourth seed Elina Svitolina with a shock 6-3, 7-5 victory. Though the world No. 3-ranked Zverev has won eight career titles-including three ATP Masters 1000 crowns-he has yet to find success at the Grand Slam level.
"I'm young. I might as well stay on court and entertain you guys", the 21-year-old Zverev joked with the crowd in Paris. "All the hours in the gym have paid off". "I'm very happy about being in the quarterfinals here going the hard way, going the long distance. showing everybody that I can play for as long as I need to". But he then picked himself up with Dzumhur's help.
The 31-year-old former world number one struggled at times on Suzanne Lenglen court, but eventually came through the four-set battle in three hours and 48 minutes.
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Despite the setback Zverev won an assured tiebreak, which included back-to-back backhand winners in the early stages, only for Khachanov to regain the upper hand in the match with two breaks in the third set.
Clearly this was incidental contact, but Dzumhur ended up with the loss to the No. 2 seeded Zverev in five sets.
Alexander Zverev of Germany celebrates winning against Karen Khachanov of Russian Federation during their men's round of 16 match during the French Open tennis tournament at Roland Garros in Paris, France.
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