Uruguay ran away as winners in their opener but would expect a better show from their attackers next when they go up against Saudi Arabia in their second game on Wednesday.
"He was fit to play against Uruguay but the coach did not want to take the risk", said the EFA.
Uruguay coach Oscar Tabarez, meanwhile, has selected star strikers Luis Suarez and Edinson Cavani in the first 11, while Atletico Madrid defenders Diego Godin and Jose Gimenez and ex-Barcelona man Martin Caceres line up in defence.
The Egyptian Pharaohs dearly missed the services of talisman Mohamed "Mo" Salah, who has been nursing a shoulder injury since falling awkwardly on May 26 during the UEFA Champions league final.
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However, Uruguay had failed to win any of their opening games at the last six World Cups they played in, while Egypt's two previous opening games were also winless.
Salah injured his left shoulder in the Champions League final last month, putting his World Cup in doubt.
The first match of the group and the tournament saw World Cup host Russian Federation unexpectedly blast Saudi Arabia by a count of 5-0 on Thursday.
"We can confirm that 32,278 tickets have been allocated for the match between Egypt and Uruguay in Yekaterinburg. But we had matches in qualifying without Suarez and Cavani, and that's just how it is".
With its traditional defensive tactics preferred by Cuper, Egypt badly needs Salah and his goals to succeed. With a victory, Uruguay could reach the next stage with a game in hand against host Russian Federation on June 25.
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Egypt faces host Russian Federation in St. Petersburg on Tuesday, and then takes on Saudi Arabia on June 25.
We look at the three key things learned following day one of the 2018 World Cup.
Finally, Uruguay broke the dead-lock from an unlikely source of defender Jose Gimenez who jumped to meet a cross from the right side of the pitch to sent the ball nestling in the net.
He thumped the turf on 73 minutes when Elshenawy smothered at his feet, and seven minutes from the end the stopper was at it again, palming Cavani's drive over.
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