A police spokesman said: 'Southgate Tube station is now closed whilst officers respond to a suspicious package.
The force added: "Enquires are ongoing to establish the cause of the reported explosion, which appears to have been minor".
People in the area are reportedly being told to stay indoors as officers work to determine the nature of the item.
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"We have treated three patients at the scene for minor injuries and have taken two people to hospital".
Trains are now not stopping at Southgate Tube station due to concerns over the suspicious package.
Emergency services including specialist police were scrambled to Southgate tube station just after 7pm.
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"I was at Southgate Station when this commotion started".
The Metropolitan Police has said it believes a "battery short circuit" is to blame for a "minor explosion" at Southgate Tube station in North London on Tuesday evening that left several people injured. I was outside the station about to enter the 125 bus. British Transport Police said the incident was not thought to be terror-related.
Scotland Yard said officers remained at the scene along with colleagues from British Transport Police, London Fire Brigade and the London Ambulance Service.
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London police are investigating a small explosion at a London Underground station.